BDBM50090940 3-(2-{4-[3-(2,6-Dichloro-phenyl)-5-methyl-isoxazol-4-ylmethoxy]-2,6-dimethyl-phenyl}-vinyl)-benzoic acid::CHEMBL319544

SMILES Cc1onc(c1COc1cc(C)c(\C=C\c2cccc(c2)C(O)=O)c(C)c1)-c1c(Cl)cccc1Cl

InChI Key InChIKey=ODSSNBPRHXSYQI-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50090940   

TargetBile acid receptor(Human)
Glaxo Wellcome Research & Development

Curated by ChEMBL
LigandPNGBDBM50090940(3-(2-{4-[3-(2,6-Dichloro-phenyl)-5-methyl-isoxazol...)
Affinity DataEC50:  70nMAssay Description:Ligand dependent recruitment of SRC1(676-700) peptide to human Farnesoid X-activated receptor by fluorescence resonance energy transfer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Glaxo Wellcome Research & Development

Curated by ChEMBL
LigandPNGBDBM50090940(3-(2-{4-[3-(2,6-Dichloro-phenyl)-5-methyl-isoxazol...)
Affinity DataEC50:  70nMAssay Description:Agonist activity at FXR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Glaxo Wellcome Research & Development

Curated by ChEMBL
LigandPNGBDBM50090940(3-(2-{4-[3-(2,6-Dichloro-phenyl)-5-methyl-isoxazol...)
Affinity DataEC50:  4.10E+3nMAssay Description:Agonist activity at FXR (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed