BDBM50091304 CHEMBL3582221

SMILES OCc1cc2c(cn1)[nH]c1ncc(cc21)-c1ccc(CN2CCCCC2)cc1

InChI Key InChIKey=MUWHBCPTIZWOPV-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50091304   

TargetSerine/threonine-protein kinase Chk1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50091304(CHEMBL3582221)
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant Chk1 using biotinylated AKT substrate after 30 mins by Alphascreen biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50091304(CHEMBL3582221)
Affinity DataEC50:  447nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as phosphorylation of histone H3 after 24 hrs by checkpoint abrogation cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed