BDBM50091712 CHEMBL3582400

SMILES Fc1ccc(cc1)-c1n[nH]c2ncc(cc12)C#Cc1c(F)ccc(NS(=O)(=O)c2cccnc2)c1F

InChI Key InChIKey=BMIRKZGQCVLNBO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50091712   

TargetSerine/threonine-protein kinase B-raf(Human)
Guangzhou Institutes of Biomedicine and Health

Curated by ChEMBL
LigandPNGBDBM50091712(CHEMBL3582400)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant B-Raf V600E mutant by FRET-based Z'-lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Guangzhou Institutes of Biomedicine and Health

Curated by ChEMBL
LigandPNGBDBM50091712(CHEMBL3582400)
Affinity DataIC50: 21nMAssay Description:Inhibition of GST-tagged recombinant human B-RAF V600E mutant expressed in baculovirus expression system incubated for 1 hr in presence of ATP by FRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed