BDBM50092036 CHEMBL304991::N-{4-[2-((R)-2-Hydroxy-2-pyridin-3-yl-ethylamino)-ethyl]-phenyl}-4-[4-(4-trifluoromethoxy-benzyl)-[1,2,3]triazol-2-yl]-benzenesulfonamide

SMILES O[C@@H](CNCCc1ccc(NS(=O)(=O)c2ccc(cc2)-n2ncc(Cc3ccc(OC(F)(F)F)cc3)n2)cc1)c1cccnc1

InChI Key InChIKey=UTVXTXZVGPURRH-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50092036   

TargetBeta-2 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50092036(N-{4-[2-((R)-2-Hydroxy-2-pyridin-3-yl-ethylamino)-...)
Affinity DataIC50: 860nMAssay Description:Binding affinity for clone human Beta-2 adrenergic receptor from CHO cell membranes in the presence of I-iodocyanopindololMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50092036(N-{4-[2-((R)-2-Hydroxy-2-pyridin-3-yl-ethylamino)-...)
Affinity DataIC50: 2.60E+3nMAssay Description:Binding affinity for cloned human Beta-1 adrenergic receptor expressed in CHO cells, tested in the presence of I-iodocyanopindolol.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50092036(N-{4-[2-((R)-2-Hydroxy-2-pyridin-3-yl-ethylamino)-...)
Affinity DataEC50:  4.10nMAssay Description:Tested in vitro for its ability to stimulate increase in cAMP in CHO cells expressing the cloned human beta-3 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed