BDBM50092095 CHEMBL324568::[16-Acetylamino-4-carbamoyl-13-(3-guanidino-propyl)-14-methyl-6,9,12,15-tetraoxo-1,2-dithia-5,8,11,14-tetraaza-cycloheptadec-7-yl]-acetic acid (SK&F 106760)

SMILES CN1[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CSSC[C@H](NC(C)=O)C1=O)C(N)=O

InChI Key InChIKey=WZFJXIKSGKCGRW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50092095   

TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50092095([16-Acetylamino-4-carbamoyl-13-(3-guanidino-propyl...)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of [125]fibrinogen binding to alpha IIb beta-3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50092095([16-Acetylamino-4-carbamoyl-13-(3-guanidino-propyl...)
Affinity DataIC50: 90nMAssay Description:Inhibition of canine platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50092095([16-Acetylamino-4-carbamoyl-13-(3-guanidino-propyl...)
Affinity DataIC50: 230nMAssay Description:Inhibition of human platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50092095([16-Acetylamino-4-carbamoyl-13-(3-guanidino-propyl...)
Affinity DataIC50: 480nMAssay Description:Inhibition of fibrinogen binding to alpha IIb beta-3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed