BDBM50092224 3-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyrimidin-7-yl]-cyclopentanol::CHEMBL69129

SMILES Nc1ncnc2n(cc(-c3ccc(Oc4ccccc4)cc3)c12)C1CCC(O)C1

InChI Key InChIKey=UJWXPHLWGVGIBB-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50092224   

TargetTyrosine-protein kinase Lck(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092224(3-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50: 5nMAssay Description:Inhibition of p56 Lck tyrosine kinase at 1 mM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092224(3-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Zap 70More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092224(3-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50: 85nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2 at 5 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092224(3-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50: 58nMAssay Description:Inhibition of tie-2 at 5 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092224(3-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50: 88nMAssay Description:Inhibition of src at 5 mM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092224(3-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50: 1nMAssay Description:Inhibition of p56 Lck tyrosine kinase catalytic domain at 5 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50092224(3-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of PKCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50092224(3-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CDC2/CyBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092224(3-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50: 544nMAssay Description:Inhibition of p56 Lck tyrosine kinase catalytic domain at 1 mM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092224(3-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50: 1nMAssay Description:Inhibition of p56 Lck tyrosine kinase at 5 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed