BDBM50092230 7-Cyclopentyl-5-(2-phenoxy-phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine::CHEMBL68774

SMILES Nc1ncnc2n(cc(-c3ccccc3Oc3ccccc3)c12)C1CCCC1

InChI Key InChIKey=PAHKLGUKLSFIBQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50092230   

TargetTyrosine-protein kinase Lck(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092230(7-Cyclopentyl-5-(2-phenoxy-phenyl)-7H-pyrrolo[2,3-...)
Affinity DataIC50: 390nMAssay Description:Inhibition of p56 Lck tyrosine kinase at 1 mM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092230(7-Cyclopentyl-5-(2-phenoxy-phenyl)-7H-pyrrolo[2,3-...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2 at 5 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092230(7-Cyclopentyl-5-(2-phenoxy-phenyl)-7H-pyrrolo[2,3-...)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of tie-2 at 5 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed