BDBM50092664 CHEMBL126819::N,N-Diethyl-4-(piperazin-1-yl-quinolin-7-yl-methyl)-benzamide

SMILES CCN(CC)C(=O)c1ccc(cc1)C(N1CCNCC1)c1ccc2cccnc2c1

InChI Key InChIKey=BAFDHSPBWFCCGG-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50092664   

TargetDelta-type opioid receptor(Human)
Astrazeneca R&D Montreal

Curated by ChEMBL
LigandPNGBDBM50092664(N,N-Diethyl-4-(piperazin-1-yl-quinolin-7-yl-methyl...)
Affinity DataIC50: 1.10nMAssay Description:Binding affinity against human opioid receptor delta 1 using [125I]-[D-Ala2]-deltorphin II as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Astrazeneca R&D Montreal

Curated by ChEMBL
LigandPNGBDBM50092664(N,N-Diethyl-4-(piperazin-1-yl-quinolin-7-yl-methyl...)
Affinity DataEC50:  6.90nMAssay Description:Agonist potency was measured using GTP gamma-[35S] binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Astrazeneca R&D Montreal

Curated by ChEMBL
LigandPNGBDBM50092664(N,N-Diethyl-4-(piperazin-1-yl-quinolin-7-yl-methyl...)
Affinity DataIC50: 1.02E+3nMAssay Description:Binding affinity against cloned human Opioid receptor mu 1 using [125I]FK33824 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Astrazeneca R&D Montreal

Curated by ChEMBL
LigandPNGBDBM50092664(N,N-Diethyl-4-(piperazin-1-yl-quinolin-7-yl-methyl...)
Affinity DataIC50: 3.16E+3nMAssay Description:Binding affinity against cloned human Opioid receptor kappa 1 using [125I]-D-Pro10-dynorphin A[1-11] as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed