BDBM50092702 CHEMBL129693::N,N-Diethyl-4-[(4-methylsulfanyl-phenyl)-piperidin-4-ylidene-methyl]-benzamide

SMILES [#6]-[#6]-[#7](-[#6]-[#6])-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1/[#6]-[#6]-[#7]-[#6]-[#6]-1)\c1ccc(-[#16]-[#6])cc1

InChI Key InChIKey=FAFHZFVBXBWGRX-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50092702   

TargetDelta-type opioid receptor(Human)
Astrazeneca R&D Montreal

Curated by ChEMBL
LigandPNGBDBM50092702(N,N-Diethyl-4-[(4-methylsulfanyl-phenyl)-piperidin...)
Affinity DataIC50: 2.10nMAssay Description:Binding affinity on cloned opioid receptor delta 1 in human HEK293S cells using [125I]-[D-Ala2]-deltorphin II as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Astrazeneca R&D Montreal

Curated by ChEMBL
LigandPNGBDBM50092702(N,N-Diethyl-4-[(4-methylsulfanyl-phenyl)-piperidin...)
Affinity DataEC50:  23nMAssay Description:Effective concentration as delta agonist potency using [35S]GTP-gamma-S binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Astrazeneca R&D Montreal

Curated by ChEMBL
LigandPNGBDBM50092702(N,N-Diethyl-4-[(4-methylsulfanyl-phenyl)-piperidin...)
Affinity DataIC50: 6.76E+3nMAssay Description:Binding affinity on cloned opioid receptor mu 1 in human HEK293S cells using [125I]FK33824 as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Astrazeneca R&D Montreal

Curated by ChEMBL
LigandPNGBDBM50092702(N,N-Diethyl-4-[(4-methylsulfanyl-phenyl)-piperidin...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity on cloned opioid receptor kappa 1 in human HEK293S cells using [125I]-D-Pro10-dynorphin A[1-11] as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed