BDBM50092771 CHEMBL3586399

SMILES CO[C@H]1CC[C@H](CN2C(=O)CNc3ncc(nc23)-c2ccc(nc2)C(C)(C)O)CC1

InChI Key InChIKey=KXDXRGGNJRTDPF-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50092771   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Celgene

Curated by ChEMBL

LigandBDBM50092771(CHEMBL3586399)Copy SMILESCopy InChI

Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of PI3K-alpha (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
10/12/2016
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetSerine/threonine-protein kinase mTOR(Human)
Celgene

Curated by ChEMBL

LigandBDBM50092771(CHEMBL3586399)Copy SMILESCopy InChI

Affinity DataIC50: 97nMAssay Description:Inhibition of mTOR (unknown origin) by HTR-FRET substrate phosphorylation assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
10/12/2016
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL