BDBM50093038 1-(3',4',5'-Trimethoxy-biphenyl-4-ylmethyl)-1,2,3,4-tetrahydro-isoquinoline-6,7-diol::CHEMBL421871

SMILES COc1cc(cc(OC)c1OC)-c1ccc(CC2NCCc3cc(O)c(O)cc23)cc1

InChI Key InChIKey=UFPJRJORSDHDFB-UHFFFAOYSA-N

Data  2 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50093038   

TargetBeta-2 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50093038(1-(3',4',5'-Trimethoxy-biphenyl-4-ylmethyl)-1,2,3,...)
Affinity DataEC50:  1.50E+3nMAssay Description:Compound was evaluated for its inhibitory activity against human beta-2 adrenergic receptor (AR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50093038(1-(3',4',5'-Trimethoxy-biphenyl-4-ylmethyl)-1,2,3,...)
Affinity DataIC50: 1.80E+3nMAssay Description:Compound was evaluated for its inhibitory activity against CHO cells expressing the cloned human beta-1 adrenergic receptor (AR) in the presence of [...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50093038(1-(3',4',5'-Trimethoxy-biphenyl-4-ylmethyl)-1,2,3,...)
Affinity DataEC50:  27nMAssay Description:Inhibitory activity against human beta-3 adrenergic receptor (AR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50093038(1-(3',4',5'-Trimethoxy-biphenyl-4-ylmethyl)-1,2,3,...)
Affinity DataIC50: 760nMAssay Description:Inhibitory activity against CHO cells expressing human Beta-2 adrenergic receptor with [125I]-iodocyanopindololMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50093038(1-(3',4',5'-Trimethoxy-biphenyl-4-ylmethyl)-1,2,3,...)
Affinity DataEC50:  6.10E+3nMAssay Description:Compound was evaluated for its inhibitory activity against human beta-1 adrenergic receptor (AR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed