BDBM50093057 (R)-5-Guanidino-2-phenylmethanesulfonylamino-pentanoic acid [((S)-3-carbamimidoyl-2-hydroxy-cyclohexylcarbamoyl)-methyl]-methyl-amide::CHEMBL431985

SMILES CN(CC(=O)N[C@H]1CCCC(C1O)C(N)=N)C(=O)[C@@H](CCCNC(N)=N)NS(=O)(=O)Cc1ccccc1

InChI Key InChIKey=ABJUGLXDGYDGLY-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50093057   

TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50093057((R)-5-Guanidino-2-phenylmethanesulfonylamino-penta...)
Affinity DataIC50: 0.860nMAssay Description:Inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50093057((R)-5-Guanidino-2-phenylmethanesulfonylamino-penta...)
Affinity DataIC50: 3.40nMAssay Description:In vitro inhibitory activity against prothrombinase (PTase) complexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50093057((R)-5-Guanidino-2-phenylmethanesulfonylamino-penta...)
Affinity DataIC50: 75nMAssay Description:In vitro inhibitory activity against Human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50093057((R)-5-Guanidino-2-phenylmethanesulfonylamino-penta...)
Affinity DataIC50: 1.20E+3nMAssay Description:In vitro inhibitory activity against plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50093057((R)-5-Guanidino-2-phenylmethanesulfonylamino-penta...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibitory activity against Thrombin (FIIa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed