BDBM50093140 CHEMBL43463::Derivative of piperazine-1-carboxylic acid 5-(piperazine-1-carbonyloxy)-cyclooctyl ester

SMILES O=C(NCc1ccccc1)N1CCN(CC1)C(=O)O[C@H]1CCC[C@H](CCC1)OC(=O)N1CCN(CC1)C(=O)NCc1ccccc1

InChI Key InChIKey=QYWNCNJGCKTVTQ-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50093140   

TargetProthrombin(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093140(Derivative of piperazine-1-carboxylic acid 5-(pipe...)
Affinity DataKi:  1.40E+4nMAssay Description:Inhibitory potency against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093140(Derivative of piperazine-1-carboxylic acid 5-(pipe...)
Affinity DataKi:  1.40E+4nMAssay Description:Compound was evaluated for its inhibitory potency against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093140(Derivative of piperazine-1-carboxylic acid 5-(pipe...)
Affinity DataKi:  4.40E+4nMAssay Description:Inhibitory potency against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093140(Derivative of piperazine-1-carboxylic acid 5-(pipe...)
Affinity DataKi:  4.40E+4nMAssay Description:Compound was evaluated for its inhibitory potency against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093140(Derivative of piperazine-1-carboxylic acid 5-(pipe...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibitory potency against plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTryptase beta-2(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093140(Derivative of piperazine-1-carboxylic acid 5-(pipe...)
Affinity DataKi:  1.01E+5nMAssay Description:Inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093140(Derivative of piperazine-1-carboxylic acid 5-(pipe...)
Affinity DataKi: >1.00E+6nMAssay Description:Compound was evaluated for its inhibitory potency against plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTryptase beta-2/delta/gamma(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093140(Derivative of piperazine-1-carboxylic acid 5-(pipe...)
Affinity DataKi:  1.01E+5nMAssay Description:Evaluated for its inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed