BDBM50093180 CHEMBL312023::Derivative of piperazine-1-carboxylic acid 5-(piperazine-1-carbonyloxy)-cyclooctyl ester

SMILES NCC12CCC(CNC(=O)N3CCN(CC3)C(=O)O[C@H]3CCC[C@H](CCC3)OC(=O)N3CCN(CC3)C(=O)NCC34CCC(CN)(CC3)CC4)(CC1)CC2

InChI Key InChIKey=KDLUBAQRBALVKK-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50093180   

TargetTryptase beta-2/delta/gamma(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093180(Derivative of piperazine-1-carboxylic acid 5-(pipe...)
Affinity DataKi:  300nMAssay Description:Evaluated for its inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093180(Derivative of piperazine-1-carboxylic acid 5-(pipe...)
Affinity DataKi:  9.50E+4nMAssay Description:Compound was evaluated for its inhibitory potency against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093180(Derivative of piperazine-1-carboxylic acid 5-(pipe...)
Affinity DataKi: >1.00E+6nMAssay Description:Compound was evaluated for its inhibitory potency against plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093180(Derivative of piperazine-1-carboxylic acid 5-(pipe...)
Affinity DataKi: >1.00E+6nMAssay Description:Compound was evaluated for its inhibitory potency against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed