BDBM50093318 4-{4-[5-(2,6-Dimethyl-piperidin-1-yl)-pentyl]-3-oxo-3,4-dihydro-2H-benzo[1,4]oxazin-2-yl}-benzamidine::CHEMBL130420

SMILES CC1CCCC(C)N1CCCCCN1C(=O)C(Oc2ccccc12)c1ccc(cc1)C(N)=N

InChI Key InChIKey=YPXOVUQIYGTCJX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50093318   

TargetProthrombin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093318(4-{4-[5-(2,6-Dimethyl-piperidin-1-yl)-pentyl]-3-ox...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093318(4-{4-[5-(2,6-Dimethyl-piperidin-1-yl)-pentyl]-3-ox...)
Affinity DataIC50: 7.90E+3nMAssay Description:In vitro inhibition of coagulation factor Xa.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093318(4-{4-[5-(2,6-Dimethyl-piperidin-1-yl)-pentyl]-3-ox...)
Affinity DataIC50: 1.30E+4nMAssay Description:In vitro inhibitory activity against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed