BDBM50093462 CHEMBL3586689

SMILES CC1=Cc2cccc(c2NC1=O)NCCN(C)C

InChI Key InChIKey=RIMSJTCQEYACPJ-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50093462   

TargetBromodomain-containing protein 4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50093462(CHEMBL3586689)
Affinity DataIC50: 2.51E+4nMAssay Description:Displacement of I-BET762 from 6His-Thr-BRD4 (1 to 477) BD1 (unknown origin) harboring BD2 Y390A mutant after 30 mins by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2016
Entry Details Article
PubMed
TargetATPase family AAA domain-containing protein 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50093462(CHEMBL3586689)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of histone H4 peptide from FLAG-6His-Tev-ATAD2 (981 to 1121) (unknown origin) expressed in Escherichia coli BL21 (DE3) after 30 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)