BDBM50093982 4-(6-Chloro-benzo[1,3]dioxol-5-ylmethyl)-2-cyclohexylmethyl-5-(4-methoxy-phenyl)-2H-pyrazole-3-carboxylic acid::CHEMBL315788

SMILES COc1ccc(cc1)-c1nn(CC2CCCCC2)c(C(O)=O)c1Cc1cc2OCOc2cc1Cl

InChI Key InChIKey=RMWPSJXRIZVXFS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50093982   

TargetEndothelin receptor type B(Rat)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50093982(4-(6-Chloro-benzo[1,3]dioxol-5-ylmethyl)-2-cyclohe...)
Affinity DataIC50: 178nMAssay Description:In vitro binding affinity to endothelin B receptor in rat cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50093982(4-(6-Chloro-benzo[1,3]dioxol-5-ylmethyl)-2-cyclohe...)
Affinity DataIC50: 2.30E+3nMAssay Description:In vitro binding affinity to endothelin A receptor in rat heart ventriclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed