BDBM50094076 CHEMBL434654::N-[4-(7-Chloro-2,3,4,5-tetrahydro-benzo[b]azepine-1-carbonyl)-3-methyl-phenyl]-2-o-tolyloxy-acetamide

SMILES Cc1ccccc1OCC(=O)Nc1ccc(C(=O)N2CCCCc3cc(Cl)ccc23)c(C)c1

InChI Key InChIKey=XCKIZAMEEBGGQB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50094076   

TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094076(N-[4-(7-Chloro-2,3,4,5-tetrahydro-benzo[b]azepine-...)
Affinity DataIC50: 0.950nMAssay Description:Concentration which inhibit [3H]AVP binding to human Vasopressin V2 receptor coded HeLa cells by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Rat)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094076(N-[4-(7-Chloro-2,3,4,5-tetrahydro-benzo[b]azepine-...)
Affinity DataIC50: 38nMAssay Description:Binding affinity towards rat Vasopressin V2 receptor after peroral administration of the compoundMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Rat)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094076(N-[4-(7-Chloro-2,3,4,5-tetrahydro-benzo[b]azepine-...)
Affinity DataIC50: 5.10E+3nMAssay Description:Binding affinity towards rat Vasopressin V1a receptor after peroral administration of the compoundMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed