BDBM50094261 CHEMBL3589968::US10544136, Compound 8

SMILES COc1ccc(cc1)-c1nc(no1)-c1ccccc1

InChI Key InChIKey=ZLFJTVYJKNIKBW-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50094261   

TargetBile acid receptor(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50094261(CHEMBL3589968 | US10544136, Compound 8)
Affinity DataIC50: 1.64E+4nMAssay Description:Antagonist activity at human full length FXR expressed in HeLa cells cotransfected with pSG5-human RXR after 24 hrs by Dual-Glo luciferase reporter g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2016
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
The Scripps Research Institute

US Patent
LigandPNGBDBM50094261(CHEMBL3589968 | US10544136, Compound 8)
Affinity DataEC50:  7.30E+4nMAssay Description:The method involves contacting the receptor with a suitable concentration of an inventive compound to bring about activation of the receptor. The con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent