BDBM50094281 1-(5-Ethynyl-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione::CHEMBL141583

SMILES Cc1cn([C@H]2C[C@@H](O)[C@@](CO)(O2)C#C)c(=O)[nH]c1=O

InChI Key InChIKey=LLKVXAAJAGWZGF-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50094281   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Tohoku University

Curated by ChEMBL
LigandPNGBDBM50094281(1-(5-Ethynyl-4-hydroxy-5-hydroxymethyl-tetrahydro-...)
Affinity DataEC50:  240nMAssay Description:Tested in vitro against HIV-1 MDR using MAGI assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Tohoku University

Curated by ChEMBL
LigandPNGBDBM50094281(1-(5-Ethynyl-4-hydroxy-5-hydroxymethyl-tetrahydro-...)
Affinity DataEC50:  610nMAssay Description:Tested in vitro against HIV-1 LAI from MT-4 cells using MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed