BDBM50094521 1,1,1-Trifluoro-3-[phenyl-(3-trifluoromethyl-benzyl)-amino]-propan-2-ol::1,1,1-trifluoro-3-(phenyl(3-(trifluoromethyl)benzyl)amino)propan-2-ol::3-((3-(trifluoromethyl)benzyl)(phenyl)amino)-1,1,1-trifluoropropan-2-ol::CHEMBL127187

SMILES OC(CN(Cc1cccc(c1)C(F)(F)F)c1ccccc1)C(F)(F)F

InChI Key InChIKey=NMRRDQBVICTNEI-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50094521   

TargetCholesteryl ester transfer protein(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50094521(1,1,1-trifluoro-3-(phenyl(3-(trifluoromethyl)benzy...)
Affinity DataIC50: 2.00E+5nMAssay Description:Tested for inhibiting CETP-mediated transfer of [3H]-CE from HDL to LDL in vitro under buffered assay conditions in human serum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50094521(1,1,1-trifluoro-3-(phenyl(3-(trifluoromethyl)benzy...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of recombinant human CETP-mediated transfer of [3H]CE from HDL to LDLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50094521(1,1,1-trifluoro-3-(phenyl(3-(trifluoromethyl)benzy...)
Affinity DataIC50: 1.50E+4nMAssay Description:Concentration required for 50% inhibition of cholesteryl ester transfer protein in presence of buffer.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50094521(1,1,1-trifluoro-3-(phenyl(3-(trifluoromethyl)benzy...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of CETPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Rabbit)
Al-Zaytoonah Private University of Jordan

Curated by ChEMBL
LigandPNGBDBM50094521(1,1,1-trifluoro-3-(phenyl(3-(trifluoromethyl)benzy...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of CETP in rabbit serum after 1 hr by fluorescent cholesteryl esters transfer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed