BDBM50094871 CHEMBL3590142

SMILES [O-][N+](=O)c1cc(ccc1Nc1ccc2[nH]c(=O)[nH]c2c1)C#N

InChI Key InChIKey=XPRPKOIHGXKBLK-UHFFFAOYSA-N

Data  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50094871   

LigandPNGBDBM50094871(CHEMBL3590142)
Affinity DataIC50: 450nMAssay Description:Inhibition of LRRK2 G2019S mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
LigandPNGBDBM50094871(CHEMBL3590142)
Affinity DataIC50: 500nMAssay Description:Inhibition of full length LRRK2 G2019S mutant (unknown origin) by LRRKtide Adapta assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
LigandPNGBDBM50094871(CHEMBL3590142)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of full length wild type LRRK2 (unknown origin) by LRRKtide Adapta assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
LigandPNGBDBM50094871(CHEMBL3590142)
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibition of wild type LRRK2 (unknown origin) assessed as inhibition of LRRKtide phosphorylation after 120 mins by radiometric assay in presence of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
LigandPNGBDBM50094871(CHEMBL3590142)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of pcDNA5FRT-TO-GFP fused - LRRK2 G2019S mutant (unknown origin) transfected in HEK293 cells incubated for 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
LigandPNGBDBM50094871(CHEMBL3590142)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of wild type pcDNA5FRT-TO-GFP fused - LRRK2 (unknown origin) transfected in HEK293 cells incubated for 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed