BDBM50094872 CHEMBL3590143

SMILES OCCNC(=O)c1ccc(Nc2nc(-c3ccccc3)c3cc(Cl)ccc3n2)cc1

InChI Key InChIKey=NGTUBVVJEABYNO-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50094872   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Acelot

Curated by ChEMBL

LigandBDBM50094872(CHEMBL3590143)Copy SMILESCopy InChI

Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of LRRK2 G2019S mutant (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLKEGGPC cidPC sidSimilars

In Depth
Date in BDB:
10/16/2016
Entry Details Article
Copy BDB DOIPubMed
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TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Acelot

Curated by ChEMBL

LigandBDBM50094872(CHEMBL3590143)Copy SMILESCopy InChI

Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of wild type LRRK2 (unknown origin) assessed as inhibition of LRRKtide phosphorylation after 120 mins by radiometric assay in presence of ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLKEGGPC cidPC sidSimilars

In Depth
Date in BDB:
10/16/2016
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL