BDBM50095150 (R)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-(1H-indol-3-yl)-ethyl]-amide::CHEMBL329996::Endomorphin 1

SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

InChI Key InChIKey=ZEXLJFNSKAHNFH-UHFFFAOYSA-N

Data  10 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50095150   

TargetMu-type opioid receptor(Rat)
Memorial Sloan-Kettering Cancer Center

Curated by PDSP Ki Database
LigandPNGBDBM50095150(Endomorphin 1 | CHEMBL329996 | (R)-1-[(S)-2-Amino-...)
Affinity DataKi:  0.240nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
TargetMu-type opioid receptor(Rat)
Memorial Sloan-Kettering Cancer Center

Curated by PDSP Ki Database
LigandPNGBDBM50095150(Endomorphin 1 | CHEMBL329996 | (R)-1-[(S)-2-Amino-...)
Affinity DataKi:  0.660nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
TargetMu-type opioid receptor(Bovine)
Memorial Sloan-Kettering Cancer Center

Curated by PDSP Ki Database
LigandPNGBDBM50095150(Endomorphin 1 | CHEMBL329996 | (R)-1-[(S)-2-Amino-...)
Affinity DataKi:  0.670nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
TargetMu-type opioid receptor(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by PDSP Ki Database
LigandPNGBDBM50095150(Endomorphin 1 | CHEMBL329996 | (R)-1-[(S)-2-Amino-...)
Affinity DataKi:  0.680nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
TargetMu-type opioid receptor(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by PDSP Ki Database
LigandPNGBDBM50095150(Endomorphin 1 | CHEMBL329996 | (R)-1-[(S)-2-Amino-...)
Affinity DataKi:  0.940nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
TargetMu-type opioid receptor(Bovine)
Memorial Sloan-Kettering Cancer Center

Curated by PDSP Ki Database
LigandPNGBDBM50095150(Endomorphin 1 | CHEMBL329996 | (R)-1-[(S)-2-Amino-...)
Affinity DataKi:  3.20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
TargetMu-type opioid receptor(Rat)
Memorial Sloan-Kettering Cancer Center

Curated by PDSP Ki Database
LigandPNGBDBM50095150(Endomorphin 1 | CHEMBL329996 | (R)-1-[(S)-2-Amino-...)
Affinity DataKi:  5.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
TargetKappa-type opioid receptor(Bovine)
Memorial Sloan-Kettering Cancer Center

Curated by PDSP Ki Database
LigandPNGBDBM50095150(Endomorphin 1 | CHEMBL329996 | (R)-1-[(S)-2-Amino-...)
Affinity DataKi:  21nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
TargetMu-type opioid receptor(Rat)
Memorial Sloan-Kettering Cancer Center

Curated by PDSP Ki Database
LigandPNGBDBM50095150(Endomorphin 1 | CHEMBL329996 | (R)-1-[(S)-2-Amino-...)
Affinity DataKi:  54nMAssay Description:Binding affinity towards Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Memorial Sloan-Kettering Cancer Center

Curated by PDSP Ki Database
LigandPNGBDBM50095150(Endomorphin 1 | CHEMBL329996 | (R)-1-[(S)-2-Amino-...)
Affinity DataIC50: 470nMAssay Description:Concentration required for inhibition of [3H]DAMGO binding to Opioid receptor mu 1 in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Memorial Sloan-Kettering Cancer Center

Curated by PDSP Ki Database
LigandPNGBDBM50095150(Endomorphin 1 | CHEMBL329996 | (R)-1-[(S)-2-Amino-...)
Affinity DataKi:  500nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed