BDBM50095462 CHEMBL3590435::US10155765, Example 42

SMILES Cn1cc(NC(=O)c2cnn3cccnc23)c(n1)C(N)=O

InChI Key InChIKey=IJJRKPOBKLKHQA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50095462   

LigandPNGBDBM50095462(CHEMBL3590435 | US10155765, Example 42)
Affinity DataIC50: 110nMAssay Description:Inhibition of human IRAK4 assessed as phosphorylation of fluorescent peptide substrate after 30 mins by fluorescent polarization readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details Article
PubMed
LigandPNGBDBM50095462(CHEMBL3590435 | US10155765, Example 42)
Affinity DataIC50: 370nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
Go to US Patent