BDBM50095729 6-[5-(4-Ethyl-piperazine-1-carbonyl)-2-propoxy-phenyl]-1-(4-fluoro-benzyl)-1,7-dihydro-imidazo[4,5-g]quinazolin-8-one::CHEMBL356178

SMILES CCCOc1ccc(cc1-c1nc2cc3ncn(Cc4ccc(F)cc4)c3cc2c(=O)[nH]1)C(=O)N1CCN(CC)CC1

InChI Key InChIKey=FGQHYVMYRARACG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50095729   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50095729(6-[5-(4-Ethyl-piperazine-1-carbonyl)-2-propoxy-phe...)
Affinity DataIC50: 35nMAssay Description:In vitro inhibitory concentration against human platelet Phosphodiesterase 5 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed