BDBM50096445 (2R,3S)-3-{(S)-2-[(S)-2-Acetylamino-3-(1H-indol-3-yl)-propionylamino]-3-methyl-butyrylamino}-2-hydroxy-N-((8S,11S)-8-isopropyl-7,10-dioxo-2-oxa-6,9-diaza-bicyclo[11.2.2]heptadeca-1(16),13(17),14-trien-11-yl)-4-phenyl-butyramide::CHEMBL302958

SMILES CC(C)[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(C)=O)C(=O)N[C@@H](Cc1ccccc1)[C@@H](O)C(=O)N[C@H]1Cc2ccc(OCCCNC(=O)[C@@H](NC1=O)C(C)C)cc2

InChI Key InChIKey=NEFLBYBCIDVAIQ-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50096445   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50096445((2R,3S)-3-{(S)-2-[(S)-2-Acetylamino-3-(1H-indol-3-...)
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration against human immunodeficiency virus (HIV) proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50096445((2R,3S)-3-{(S)-2-[(S)-2-Acetylamino-3-(1H-indol-3-...)
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration against TL3-resistant HIV(V82A) mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50096445((2R,3S)-3-{(S)-2-[(S)-2-Acetylamino-3-(1H-indol-3-...)
Affinity DataIC50: 30nMAssay Description:Inhibitory concentration against drug-resistant HIV(V82F) mutant proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50096445((2R,3S)-3-{(S)-2-[(S)-2-Acetylamino-3-(1H-indol-3-...)
Affinity DataIC50: 49nMAssay Description:Inhibitory concentration against TL3-resistant HIV(F53L) mutant proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50096445((2R,3S)-3-{(S)-2-[(S)-2-Acetylamino-3-(1H-indol-3-...)
Affinity DataIC50: 49nMAssay Description:Inhibitory concentration against TL3-resistant HIV(L63P) mutant proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50096445((2R,3S)-3-{(S)-2-[(S)-2-Acetylamino-3-(1H-indol-3-...)
Affinity DataIC50: 49nMAssay Description:Inhibitory concentration against TL3-resistant HIV(M461) mutant proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50096445((2R,3S)-3-{(S)-2-[(S)-2-Acetylamino-3-(1H-indol-3-...)
Affinity DataIC50: 49nMAssay Description:Inhibitory concentration against TL3-resistant HIV(M461) mutant proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50096445((2R,3S)-3-{(S)-2-[(S)-2-Acetylamino-3-(1H-indol-3-...)
Affinity DataIC50: 49nMAssay Description:Inhibitory concentration against TL3-resistant HIV(V771) mutant proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50096445((2R,3S)-3-{(S)-2-[(S)-2-Acetylamino-3-(1H-indol-3-...)
Affinity DataIC50: 71nMAssay Description:Inhibitory concentration against drug-resistant HIV(G48V) mutant proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed