BDBM50096447 (2R,3S)-3-{(S)-2-[(S)-2-Acetylamino-3-(4-hydroxy-phenyl)-propionylamino]-3-methyl-butyrylamino}-2-hydroxy-N-((8S,11S)-8-isopropyl-7,10-dioxo-2-oxa-6,9-diaza-bicyclo[11.2.2]heptadeca-1(16),13(17),14-trien-11-yl)-4-phenyl-butyramide::CHEMBL74166

SMILES CC(C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(C)=O)C(=O)N[C@@H](Cc1ccccc1)[C@@H](O)C(=O)N[C@H]1Cc2ccc(OCCCNC(=O)[C@@H](NC1=O)C(C)C)cc2

InChI Key InChIKey=FLCKUBUGOFHCRF-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50096447   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50096447((2R,3S)-3-{(S)-2-[(S)-2-Acetylamino-3-(4-hydroxy-p...)
Affinity DataIC50: 6nMAssay Description:Inhibitory concentration against human immunodeficiency virus (HIV) proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50096447((2R,3S)-3-{(S)-2-[(S)-2-Acetylamino-3-(4-hydroxy-p...)
Affinity DataIC50: 11nMAssay Description:Inhibitory concentration against TL3-resistant HIV(V82A) mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50096447((2R,3S)-3-{(S)-2-[(S)-2-Acetylamino-3-(4-hydroxy-p...)
Affinity DataIC50: 26nMAssay Description:Inhibitory concentration against drug-resistant HIV(V82F) mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50096447((2R,3S)-3-{(S)-2-[(S)-2-Acetylamino-3-(4-hydroxy-p...)
Affinity DataIC50: 57nMAssay Description:Inhibitory concentration against drug-resistant HIV(G48V) mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50096447((2R,3S)-3-{(S)-2-[(S)-2-Acetylamino-3-(4-hydroxy-p...)
Affinity DataIC50: 70nMAssay Description:Inhibitory concentration against TL3-resistant HIV(M461) mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50096447((2R,3S)-3-{(S)-2-[(S)-2-Acetylamino-3-(4-hydroxy-p...)
Affinity DataIC50: 70nMAssay Description:Inhibitory concentration against TL3-resistant HIV(F53L) mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50096447((2R,3S)-3-{(S)-2-[(S)-2-Acetylamino-3-(4-hydroxy-p...)
Affinity DataIC50: 70nMAssay Description:Inhibitory concentration against TL3-resistant HIV(V771) mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50096447((2R,3S)-3-{(S)-2-[(S)-2-Acetylamino-3-(4-hydroxy-p...)
Affinity DataIC50: 70nMAssay Description:Inhibitory concentration against TL3-resistant HIV(L241) mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50096447((2R,3S)-3-{(S)-2-[(S)-2-Acetylamino-3-(4-hydroxy-p...)
Affinity DataIC50: 70nMAssay Description:Inhibitory concentration against TL3-resistant HIV(L63P) mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed