BDBM50096595 4-{[(2-{(4-Chloro-benzyl)-[2-(3-{1-[3-ethoxycarbonylmethyl-4-oxo-2-thioxo-thiazolidin-(5Z)-ylidene]-ethyl}-phenoxycarbonylamino)-4-methyl-pentanoyl]-amino}-ethyl)-amino-methyl]di-benzoic acid methyl ester::CHEMBL176355

SMILES CCOC(=O)Cn1c(O)c(sc1=S)C(=C)c1cccc(OC(=O)N[C@@H](CC(C)C)C(=O)N(CCN(Cc2ccc(cc2)C(=O)OC)Cc2ccc(cc2)C(=O)OC)Cc2ccc(Cl)cc2)c1

InChI Key InChIKey=BQPAYEJODNZYNN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50096595   

TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Institute of Molecular and Cell Biology

Curated by ChEMBL
LigandPNGBDBM50096595(4-{[(2-{(4-Chloro-benzyl)-[2-(3-{1-[3-ethoxycarbon...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibitory activity against hepatitis C virus (HCV) NS3 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Institute of Molecular and Cell Biology

Curated by ChEMBL
LigandPNGBDBM50096595(4-{[(2-{(4-Chloro-benzyl)-[2-(3-{1-[3-ethoxycarbon...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory activity against plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Institute of Molecular and Cell Biology

Curated by ChEMBL
LigandPNGBDBM50096595(4-{[(2-{(4-Chloro-benzyl)-[2-(3-{1-[3-ethoxycarbon...)
Affinity DataIC50: 2.10E+5nMAssay Description:Inhibitory activity against Serine protease chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed