BDBM50096643 2-(Biphenyl-4-yloxymethyl)-N-hydroxy-4-(1,1,3-trioxo-1,3-dihydro-1lambda*6*-benzo[d]isothiazol-2-yl)-butyramide::CHEMBL103442

SMILES ONC(=O)C(CCN1C(=O)c2ccccc2S1(=O)=O)COc1ccc(cc1)-c1ccccc1

InChI Key InChIKey=KFTWEWMQNRZZNL-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50096643   

Target72 kDa type IV collagenase(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096643(2-(Biphenyl-4-yloxymethyl)-N-hydroxy-4-(1,1,3-trio...)
Affinity DataIC50: 7nMAssay Description:Inhibition of Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096643(2-(Biphenyl-4-yloxymethyl)-N-hydroxy-4-(1,1,3-trio...)
Affinity DataIC50: 16nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096643(2-(Biphenyl-4-yloxymethyl)-N-hydroxy-4-(1,1,3-trio...)
Affinity DataIC50: 23nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096643(2-(Biphenyl-4-yloxymethyl)-N-hydroxy-4-(1,1,3-trio...)
Affinity DataIC50: 42nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096643(2-(Biphenyl-4-yloxymethyl)-N-hydroxy-4-(1,1,3-trio...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed