BDBM50096644 2-(Biphenyl-4-yloxymethyl)-N-hydroxy-4-(1-oxo-1H-phthalazin-2-yl)-butyramide::CHEMBL102459

SMILES ONC(=O)C(CCn1ncc2ccccc2c1=O)COc1ccc(cc1)-c1ccccc1

InChI Key InChIKey=YMFBAKCSKQKFMX-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50096644   

TargetMatrix metalloproteinase-9(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096644(2-(Biphenyl-4-yloxymethyl)-N-hydroxy-4-(1-oxo-1H-p...)
Affinity DataIC50: 33nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096644(2-(Biphenyl-4-yloxymethyl)-N-hydroxy-4-(1-oxo-1H-p...)
Affinity DataIC50: 62nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096644(2-(Biphenyl-4-yloxymethyl)-N-hydroxy-4-(1-oxo-1H-p...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096644(2-(Biphenyl-4-yloxymethyl)-N-hydroxy-4-(1-oxo-1H-p...)
Affinity DataIC50: 6nMAssay Description:Inhibition of Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096644(2-(Biphenyl-4-yloxymethyl)-N-hydroxy-4-(1-oxo-1H-p...)
Affinity DataIC50: 101nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed