BDBM50096663 3-(3-Cyclopropyl-1-ethoxy-1-trifluoromethyl-prop-2-ynyl)-5-ethyl-6-methyl-1H-pyridin-2-one::CHEMBL321174

SMILES CCOC(C#CC1CC1)(c1cc(CC)c(C)[nH]c1=O)C(F)(F)F

InChI Key InChIKey=GFCFCFQXNXWQIZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50096663   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50096663(3-(3-Cyclopropyl-1-ethoxy-1-trifluoromethyl-prop-2...)
Affinity DataIC50: 183nMAssay Description:Inhibition of the NNRTI HIV-1 enzyme by 50% using enzyme assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed