BDBM50096764 CHEMBL127656::Cyanoguanidine derivative

SMILES CCCCCCCCc1csc(n1)N1CCc2c1cccc2NC(Nc1ccc(CCNC[C@H](O)c2cccnc2)cc1)=NC#N

InChI Key InChIKey=BJCLVBBSAUATBV-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50096764   

TargetBeta-2 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096764(Cyanoguanidine derivative | CHEMBL127656)
Affinity DataIC50: 930nMAssay Description:Binding affinity to the human beta-2 adrenergic receptor assayed using [125I]iodocyanopindolol as radioligand in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096764(Cyanoguanidine derivative | CHEMBL127656)
Affinity DataEC50:  13nMAssay Description:In vitro efficacy at human beta-3 adrenergic receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096764(Cyanoguanidine derivative | CHEMBL127656)
Affinity DataIC50: 1.20E+3nMAssay Description:Binding affinity towards human Beta-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed