BDBM50096767 3-(1-{4-[2-((R)-2-Hydroxy-2-pyridin-3-yl-ethylamino)-ethyl]-phenylamino}-2-nitro-vinylamino)-benzamide::CHEMBL127451

SMILES NC(=O)c1cccc(c1)\[NH+]=C(/[CH-][N+]([O-])=O)Nc1ccc(CCNCC(O)c2cccnc2)cc1

InChI Key InChIKey=RXCCKHHODKRZFP-UHFFFAOYSA-O

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50096767   

TargetBeta-3 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096767(3-(1-{4-[2-((R)-2-Hydroxy-2-pyridin-3-yl-ethylamin...)
Affinity DataEC50:  10nMAssay Description:In vitro efficacy at human beta-3 adrenergic receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096767(3-(1-{4-[2-((R)-2-Hydroxy-2-pyridin-3-yl-ethylamin...)
Affinity DataIC50: 790nMAssay Description:Binding affinity towards human Beta-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096767(3-(1-{4-[2-((R)-2-Hydroxy-2-pyridin-3-yl-ethylamin...)
Affinity DataIC50: 1.20E+3nMAssay Description:Binding affinity to the human beta-2 adrenergic receptor assayed using [125I]iodocyanopindolol as radioligand in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed