BDBM50096849 CHEMBL3580763

SMILES Cc1cc(sn1)-c1ccccc1OCCN1CCn2c(ccc(-n3cnc(C)c3)c2=O)C1=O

InChI Key InChIKey=HHXRKDBADFMRBY-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50096849   

TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50096849(CHEMBL3580763)Copy SMILESCopy InChI

Affinity DataIC50: 104nMAssay Description:Modulation of human gamma secretase overexpressed in CHO cells co-expressing wild type human APP assessed as inhibition of amyloid beta-42 production...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
10/21/2016
Entry Details Article
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