BDBM50096860 (E)-3-Biphenyl-4-yl-N-{2-[3-(2,3-dimethyl-phenylsulfamoyl)-phenylcarbamoyl]-ethyl}-acrylamide::CHEMBL423158

SMILES Cc1cccc(NS(=O)(=O)c2cccc(NC(=O)CCNC(=O)\C=C\c3ccc(cc3)-c3ccccc3)c2)c1C

InChI Key InChIKey=WMWCULCOCZVXGF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50096860   

TargetCAAX prenyl protease 2(Human)
Philipps-UniversitäT Marburg

Curated by ChEMBL
LigandPNGBDBM50096860((E)-3-Biphenyl-4-yl-N-{2-[3-(2,3-dimethyl-phenylsu...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of recombinant prenyl protein-specific protease Rce1 expressed in Sf9 cells at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50096860((E)-3-Biphenyl-4-yl-N-{2-[3-(2,3-dimethyl-phenylsu...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibitory activity against FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed