BDBM50097042 1-[2-(1H-Indol-3-yl)-ethyl]-3-thiazol-2-yl-thiourea::CHEMBL356247

SMILES S=C(NCCc1c[nH]c2ccccc12)Nc1nccs1

InChI Key InChIKey=JYLRIEYSOXMZFQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50097042   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Institute

Curated by ChEMBL
LigandPNGBDBM50097042(1-[2-(1H-Indol-3-yl)-ethyl]-3-thiazol-2-yl-thioure...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibitory activity against non-nucleoside reverse transcriptase inhibitors (NNRTI) -resistant HIV-1 strain A17 with a Y181C mutation in RT (reverse ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Institute

Curated by ChEMBL
LigandPNGBDBM50097042(1-[2-(1H-Indol-3-yl)-ethyl]-3-thiazol-2-yl-thioure...)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibitory activity against non-nucleoside reverse transcriptase inhibitors (NNRTI) -resistant HIV-1 strain A17 variant with Y181C plus K103N mutatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed