BDBM50097132 CHEMBL3580962

SMILES N[C@H]1CC[C@H](CNc2nccc(Nc3cc([nH]n3)C3CC3)n2)CC1

InChI Key InChIKey=TUBDCTXNBUJRCI-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50097132   

TargetSerine/threonine-protein kinase PAK 1(Human)
Shanghai Chempartner

Curated by ChEMBL
LigandPNGBDBM50097132(CHEMBL3580962)
Affinity DataKi:  26nMAssay Description:Inhibition of human recombinant PAK1 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate assessed as substrate phosphorylation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 4(Human)
Shanghai Chempartner

Curated by ChEMBL
LigandPNGBDBM50097132(CHEMBL3580962)
Affinity DataKi:  38nMAssay Description:Inhibition of human recombinant PAK4 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate assessed as substrate phosphorylation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 1(Human)
Shanghai Chempartner

Curated by ChEMBL
LigandPNGBDBM50097132(CHEMBL3580962)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of PAK1 in human EBC1 cells assessed as inhibition of MEK phosphorylation at S298 after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMed