BDBM50097257 (R)-N*4*-Hydroxy-N*1*-[(S)-1-((R)-indan-1-ylcarbamoyl)-2-(1H-indol-3-yl)-ethyl]-2-isobutyl-succinamide::CHEMBL152104

SMILES CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H]1CCc2ccccc12

InChI Key InChIKey=FGDQQAHGMHOQDV-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50097257   

Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097257((R)-N*4*-Hydroxy-N*1*-[(S)-1-((R)-indan-1-ylcarbam...)
Affinity DataKi:  100nMAssay Description:Inhibition of Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Glycomed

Curated by ChEMBL
LigandPNGBDBM50097257((R)-N*4*-Hydroxy-N*1*-[(S)-1-((R)-indan-1-ylcarbam...)
Affinity DataKi:  100nMAssay Description:The compound was tested for its binding affinity towards 92 kDa gelatinase (Matrix metalloprotease-9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Glycomed

Curated by ChEMBL
LigandPNGBDBM50097257((R)-N*4*-Hydroxy-N*1*-[(S)-1-((R)-indan-1-ylcarbam...)
Affinity DataKi:  130nMAssay Description:The compound was tested for its binding affinity towards neutrophil collagenase (Matrix metalloprotease-8)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097257((R)-N*4*-Hydroxy-N*1*-[(S)-1-((R)-indan-1-ylcarbam...)
Affinity DataKi:  240nMAssay Description:Binding affinity towards 72 kDa gelatinase (Matrix metalloprotease-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097257((R)-N*4*-Hydroxy-N*1*-[(S)-1-((R)-indan-1-ylcarbam...)
Affinity DataKi:  580nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed