BDBM50097267 (R)-N*1*-[(S)-1-(benzhydryl-carbamoyl)-2,2-dimethyl-propyl]-2-[3-(2-fluoro-biphenyl-4-yl)-propyl]-N*4*-hydroxy-succinamide::CHEMBL443818

SMILES CC(C)(C)[C@H](NC(=O)[C@H](CCCc1ccc(c(F)c1)-c1ccccc1)CC(=O)NO)C(=O)NC(c1ccccc1)c1ccccc1

InChI Key InChIKey=ZWHGWUJFPYMQHK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50097267   

TargetStromelysin-1(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50097267((R)-N*1*-[(S)-1-(benzhydryl-carbamoyl)-2,2-dimethy...)
Affinity DataIC50: 10nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50097267((R)-N*1*-[(S)-1-(benzhydryl-carbamoyl)-2,2-dimethy...)
Affinity DataIC50: 10nMAssay Description:Concentration required to inhibit the catalytic domain Matrix metalloprotease-3 using Nagase fluorogenic as a substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097267((R)-N*1*-[(S)-1-(benzhydryl-carbamoyl)-2,2-dimethy...)
Affinity DataIC50: 41nMAssay Description:Concentration required to inhibit the catalytic domain Matrix metalloprotease-2 using Nagase fluorogenic as a substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed