BDBM50097995 5-Phenyl-7-pyrrolidin-3-yl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine::CHEMBL168829

SMILES Nc1ncnc2n(cc(-c3ccccc3)c12)C1CCNC1

InChI Key InChIKey=XNIBNLVJQPSPNT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50097995   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Novartis Pharma Research

Curated by ChEMBL
LigandPNGBDBM50097995(5-Phenyl-7-pyrrolidin-3-yl-7H-pyrrolo[2,3-d]pyrimi...)
Affinity DataIC50: 230nMAssay Description:Inhibition of p60 c-Src tyrosine kinase enzyme activity in liquid-phase tyrosine phosphorylation assay at 830 ng/mLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Novartis Pharma Research

Curated by ChEMBL
LigandPNGBDBM50097995(5-Phenyl-7-pyrrolidin-3-yl-7H-pyrrolo[2,3-d]pyrimi...)
Affinity DataIC50: 1.34E+4nMAssay Description:Inhibition of epidermal growth factor receptor (EGF-R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed