BDBM50098262 2-(4'-Methoxy-biphenyl-4-sulfonylamino)-6-(2-methoxy-ethoxymethoxy)-hex-4-ynoic acid::CHEMBL10266

SMILES COCCOCOCC#CCC(NS(=O)(=O)c1ccc(cc1)-c1ccc(OC)cc1)C(O)=O

InChI Key InChIKey=DPDQSBRVGYFIHD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50098262   

TargetCollagenase 3(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098262(2-(4'-Methoxy-biphenyl-4-sulfonylamino)-6-(2-metho...)
Affinity DataIC50: 88nMpH: 7.4Assay Description:Inhibitory activity against human matrix metalloprotease-13 in quenched fluorescence assay at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098262(2-(4'-Methoxy-biphenyl-4-sulfonylamino)-6-(2-metho...)
Affinity DataIC50: 33nMpH: 7.4Assay Description:Inhibitory activity against matrix metalloprotease-2 (MMP-2) in quenched fluorescence assay at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098262(2-(4'-Methoxy-biphenyl-4-sulfonylamino)-6-(2-metho...)
Affinity DataIC50: 6.51E+3nMpH: 7.4Assay Description:Inhibitory activity against human matrix metalloprotease-1 in quenched fluorescence assay at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098262(2-(4'-Methoxy-biphenyl-4-sulfonylamino)-6-(2-metho...)
Affinity DataIC50: 2.34E+3nMpH: 7.4Assay Description:Inhibitory activity against human matrix metalloprotease-3 (MMP-3) (at pH 7.4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed