BDBM50098432 CHEMBL3593428

SMILES O=c1[nH]c2cnc3[nH]ccc3c2n1C1CCCCC1

InChI Key InChIKey=LIEFFTZBSWVRMX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50098432   

TargetTyrosine-protein kinase JAK3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50098432(CHEMBL3593428)
Affinity DataIC50: 54nMAssay Description:Inhibition of human JAK3 kinase domain using biotin-Lyn-substrate-2 as substrate and ATP incubated for 1 hr by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50098432(CHEMBL3593428)
Affinity DataIC50: 43nMAssay Description:Inhibition of human JAK2 kinase domain using biotin-Lyn-substrate-2 as substrate and ATP incubated for 1 hr by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50098432(CHEMBL3593428)
Affinity DataIC50: 79nMAssay Description:Inhibition of human JAK1 kinase domain using biotin-Lyn-substrate-2 as substrate and ATP incubated for 1 hr by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2016
Entry Details Article
PubMed