BDBM50098436 CHEMBL3593579

SMILES C[C@@H]1CCCC[C@@H]1n1c2c(cnc3[nH]ccc23)[nH]c1=O

InChI Key InChIKey=KBPMBDUSBIXQRB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50098436   

TargetTyrosine-protein kinase JAK3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50098436(CHEMBL3593579)
Affinity DataIC50: 3nMAssay Description:Inhibition of human JAK3 kinase domain using biotin-Lyn-substrate-2 as substrate and ATP incubated for 1 hr by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50098436(CHEMBL3593579)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of human JAK2 kinase domain using biotin-Lyn-substrate-2 as substrate and ATP incubated for 1 hr by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50098436(CHEMBL3593579)
Affinity DataIC50: 14nMAssay Description:Inhibition of human JAK1 kinase domain using biotin-Lyn-substrate-2 as substrate and ATP incubated for 1 hr by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2016
Entry Details Article
PubMed