BDBM50098513 4-o-Tolylsulfanyl-thieno[2,3-c]pyridine-2-carboxylic acid amide::CHEMBL6278

SMILES Cc1ccccc1Sc1cncc2sc(cc12)C(N)=O

InChI Key InChIKey=UKYJEJDOFBKSDL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50098513   

TargetE-selectin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50098513(4-o-Tolylsulfanyl-thieno[2,3-c]pyridine-2-carboxyl...)
Affinity DataIC50: 55nMAssay Description:In vitro potency against TNF alpha induced expression of Selectin E on human vascular endothelial cells using CAM ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular cell adhesion protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50098513(4-o-Tolylsulfanyl-thieno[2,3-c]pyridine-2-carboxyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro potency against TNF alpha induced expression of VCAM-1 on human vascular endothelial cells using CAM ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntercellular adhesion molecule 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50098513(4-o-Tolylsulfanyl-thieno[2,3-c]pyridine-2-carboxyl...)
Affinity DataIC50: 40nMAssay Description:In vitro potency against TNF alpha induced expression of intercellular adhesion molecule-1 on human vascular endothelial cells using CAM ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed