BDBM50098654 (4-{4-[2-Hydroxy-2-(4-hydroxy-3-methanesulfonylamino-phenyl)-ethylamino]-piperidin-1-yl}-benzoylamino)-acetic acid::CHEMBL36568

SMILES CS(=O)(=O)Nc1cc(ccc1O)[C@@H](O)CNC1CCN(CC1)c1ccc(cc1)C(=O)NCC(O)=O

InChI Key InChIKey=LSFBOYIJGPJWMG-UHFFFAOYSA-N

Data  2 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50098654   

TargetBeta-2 adrenergic receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50098654((4-{4-[2-Hydroxy-2-(4-hydroxy-3-methanesulfonylami...)
Affinity DataEC50:  40nMAssay Description:Increased cAMP levels of Chinese hamster ovary (CHO) cells expressing human beta 2 adrenergic receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50098654((4-{4-[2-Hydroxy-2-(4-hydroxy-3-methanesulfonylami...)
Affinity DataEC50:  50nMAssay Description:In vitro activity to increase cAMP levels in Chinese hamster ovary (CHO) cells expressing the cloned human beta 1 Adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50098654((4-{4-[2-Hydroxy-2-(4-hydroxy-3-methanesulfonylami...)
Affinity DataEC50:  60nMAssay Description:In vitro increase in cAMP levels in Chinese hamster ovary cells expressing the human cloned beta 3 Adrenergic receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50098654((4-{4-[2-Hydroxy-2-(4-hydroxy-3-methanesulfonylami...)
Affinity DataKi:  1.16E+4nMAssay Description:Inhibition of I-iodocyanopindolol binding to human beta 2 adrenergic receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50098654((4-{4-[2-Hydroxy-2-(4-hydroxy-3-methanesulfonylami...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of I-iodocyanopindolol binding to human beta 1 adrenergic receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed