BDBM50098659 2-(4-{4-[2-Hydroxy-2-(4-hydroxy-3-methanesulfonylamino-phenyl)-ethylamino]-piperidin-1-yl}-benzoylamino)-4-methyl-pentanoic acid::CHEMBL285881

SMILES CC(C)C[C@H](NC(=O)c1ccc(cc1)N1CCC(CC1)NC[C@H](O)c1ccc(O)c(NS(C)(=O)=O)c1)C(O)=O

InChI Key InChIKey=UCLMKQWLGHPTKX-UHFFFAOYSA-N

Data  2 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50098659   

TargetBeta-3 adrenergic receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50098659(2-(4-{4-[2-Hydroxy-2-(4-hydroxy-3-methanesulfonyla...)
Affinity DataEC50:  8nMAssay Description:In vitro increase in cAMP levels in Chinese hamster ovary cells expressing the human cloned beta 3 Adrenergic receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50098659(2-(4-{4-[2-Hydroxy-2-(4-hydroxy-3-methanesulfonyla...)
Affinity DataEC50:  60nMAssay Description:In vitro activity to increase cAMP levels in Chinese hamster ovary (CHO) cells expressing the cloned human beta 1 Adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50098659(2-(4-{4-[2-Hydroxy-2-(4-hydroxy-3-methanesulfonyla...)
Affinity DataEC50:  80nMAssay Description:Increased cAMP levels of Chinese hamster ovary (CHO) cells expressing human beta 2 adrenergic receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50098659(2-(4-{4-[2-Hydroxy-2-(4-hydroxy-3-methanesulfonyla...)
Affinity DataKi:  3.40E+3nMAssay Description:Inhibition of I-iodocyanopindolol binding to human beta 2 adrenergic receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50098659(2-(4-{4-[2-Hydroxy-2-(4-hydroxy-3-methanesulfonyla...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of I-iodocyanopindolol binding to human beta 1 adrenergic receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed