BDBM50098916 (R)-3-(4-Methoxy-benzenesulfonyl)-1-(2-methoxy-ethyl)-6-oxo-hexahydro-pyrimidine-4-carboxylic acid hydroxyamide::CHEMBL266292

SMILES COCCN1CN([C@H](CC1=O)C(=O)NO)S(=O)(=O)c1ccc(OC)cc1

InChI Key InChIKey=SUFSQYXUPYDFHG-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50098916   

TargetMatrix metalloproteinase-9(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098916((R)-3-(4-Methoxy-benzenesulfonyl)-1-(2-methoxy-eth...)
Affinity DataIC50: 53nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetMatrilysin(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098916((R)-3-(4-Methoxy-benzenesulfonyl)-1-(2-methoxy-eth...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098916((R)-3-(4-Methoxy-benzenesulfonyl)-1-(2-methoxy-eth...)
Affinity DataIC50: 696nMAssay Description:Inhibition of human Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098916((R)-3-(4-Methoxy-benzenesulfonyl)-1-(2-methoxy-eth...)
Affinity DataIC50: 102nMAssay Description:Inhibition of Matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098916((R)-3-(4-Methoxy-benzenesulfonyl)-1-(2-methoxy-eth...)
Affinity DataIC50: 180nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098916((R)-3-(4-Methoxy-benzenesulfonyl)-1-(2-methoxy-eth...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098916((R)-3-(4-Methoxy-benzenesulfonyl)-1-(2-methoxy-eth...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed