BDBM50098948 8-Chloro-3-phenyl-3,4-dihydro-isoquinolin-1-ylamine::CHEMBL7934

SMILES NC1=NC(Cc2cccc(Cl)c12)c1ccccc1

InChI Key InChIKey=QPAHGGACAIYANQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50098948   

TargetNitric oxide synthase, endothelial(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098948(8-Chloro-3-phenyl-3,4-dihydro-isoquinolin-1-ylamin...)
Affinity DataIC50: 6.00E+3nMAssay Description:Ability to inhibit conversion of [3H]L-Arg to [3H]L-citrulline catalyzed by endothelial NOS (e NOS) from HUVEC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed