BDBM50098949 5-(3,3-Dimethyl-but-1-ynyl)-4,5-dihydro-thieno[2,3-c]pyridin-7-ylamine::CHEMBL8288

SMILES CC(C)(C)C#CC1Cc2ccsc2C(N)=N1

InChI Key InChIKey=PIQOUNDYMDWDNR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50098949   

TargetNitric oxide synthase, inducible(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098949(5-(3,3-Dimethyl-but-1-ynyl)-4,5-dihydro-thieno[2,3...)
Affinity DataIC50: 3.60E+3nMAssay Description:Ability to inhibit the conversion of [3H]L-Arg to [3H]L-citrulline catalyzed by i-NOS from human DLD-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098949(5-(3,3-Dimethyl-but-1-ynyl)-4,5-dihydro-thieno[2,3...)
Affinity DataIC50: 1.00E+4nMAssay Description:Ability to inhibit the conversion of [3H]-L-Arg to [3H]L-citrulline catalyzed by n-NOS from rat cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed